Nnọọ na Sichuan Hengkang Science and Technology Development Co., Ltd.

5- (4-phenoxyphenyl) -7H-pyrrolo [2,3-d] pyriMidin-4-ylaMine

Nkọwa dị mkpirikpi:

image122

Nọmba ekwentị: 330786-24-8

MF: C17H13N5O

MW: 303.32

EINECS: 810-090-0

Ụdị ngwaahịa: Ibrutinib;Anticancer


Nkọwa ngwaahịa

Mkpado ngwaahịa

Ụdị okwu

5- (4-phenoxyphenyl) -7H-pyrrolo [2,3-d] pyriMidin-4-ylaMine

4-Amino-3- (4-phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidine.

3- (4-phenoxy-phenyl) -1 (2) H-pyrazole

3- (4-phenoxyphenyl) -1H-pyrazole

3- (4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amine

3-[4-phenoxyphenyl] pyrazole

Ibrutinib N-2

3- (4-phenoxyphenyl) -1H-pyrazolo [3,4-D] pyrimidine-4-amine

1H-Pyrazolo [3,4-d] pyrimidin-4-amine,

Njirimara physico-chemical

Usoro ihe omimi C5H8O3
Molar Mass 116,115 g / mol
Njupụta 1.262g/cm3
Ebe obi ụtọ 243.2°C na 760 mmHg
Ebe mgbari 113.2C
Uzuoku nrịbama 0.0107mmHg na 25°C
Ntụgharị ntụgharị uche 1.48

Njirimara kemịkalụ

Dike: 1.380± 0.06 g/cm3 (20 ºC 760 Torr),

SOlubility: enweghị ike soluble (1.2E-3 g/L) (25ºC),

PSA: 89.71000

Nọmba ederede: 3.97560

Ozi nchekwa

2.1 Nhazi nke ihe ma ọ bụ ngwakọta

Nnukwu nsi - Atiya 4, Oral

2.2 akara akara GHS, gụnyere nkwupụta akpachapụ anya

Foto (s)  image3
Okwu mgbaàmà Ịdọ aka ná ntị
Okwu(s) egwu H302 na-emerụ ma ọ bụrụ na iloro ya
Nkwupụta(s) ịkpachara anya 
Mgbochi P264 Sachaa ... nke ọma mgbe ejirichara ya.

P270 erila, aṅụ ma ọ bụ anwụrụ ọkụ mgbe ị na-eji ngwaahịa a.

Azịza ya P301+P317 Ọ BỤRỤ na-ejupụta: Nweta enyemaka ahụike.

P330 sachaa ọnụ.

Nchekwa onweghi
mkpofu P501 Tụfuo ọdịnaya/akpa n'ebe ọgwụgwọ kwesịrị ekwesị na ebe mkpofu dịka iwu na ụkpụrụ siri dị, yana njirimara ngwaahịa n'oge mkpofu.

Nkọwapụta ngwaahịa

Ọdịdị/agba: Ìhè isi awọ, na-acha ọcha na ìhè Brown siri ike
Nyocha: 98.0% ~ 102.0%
Profaịlụ adịghị ọcha:
IBR-4-m-OPh NMT 0.10%
IBR-4-o-OPh NMT 0.10%
NMT ọ bụla ọzọ 0.20%
Mkpokọta adịghị ọcha NMT 1.0%
Chemical ịdị ọcha (mpaghara HPLC) ≥ 99.0%
LOD (%): ≤1.0%

Uru anyị:
1 Anyị nwere ikike mbupụ iji mee ka ị na-arụ ọrụ na ụlọ ọrụ mmepụta ihe ozugbo dị.
2 Ọ bụ nke ngwaahịa dị ize ndụ anyị nwere ike ịmere gị asambodo mbupu nchekwa.
3 Anabatara ule nke ndị ọzọ.
4 Enwere ike ịnye ihe nlele tupu mbupu n'efu.


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