Nnọọ na Sichuan Hengkang Science and Technology Development Co., Ltd.

(S) -1-Boc-3-hydroxypiperidine

Nkọwa dị mkpirikpi:

image4

CAS: 143900-44-1

MF: C10H19NO3

MW: 201.26


Nkọwa ngwaahịa

Mkpado ngwaahịa

Ụdị ngwaahịa

ChiralReagents;Piperidines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Antiancer

Ụdị okwu

(S) -1-Boc-3-Hydroxypiperidine

(S)-1-N-BOC-3-HYDROXY-PIPERIDINE

(S)-3-HYDROXY-PIPERIDINE-1-CARBOXYLIC Acid TERT-BUTYL ESTER

(S)-3-HYDROXY-1-(TERT-BUTOXYCARBONYL)PIPERIDINE

(S)-1-BOC-3-PIPERIDINOL

(S)-N-(TERT-BUTOXYCARBONYL)-3-HYDROXYPIPERIDINE HYDROCHLORIDE

(S)-N-BOC-3-HYDROXY PIPERIDINE

(S)-TERT BUTYL-3-HYDROXYPIPERIDINE-1-CARBOXYLATE

(S)-1- (tert-Butoxycarbonyl) -3-hydroxypiperidine

S-1-Boc-3-hydroxypiperidine

(3S) -hydroxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester.

(S) -3,5-DifluoroMandelic acid

(S) -tert-Butyl 3-hydroxypiperidine-1-carboxylate

(S) -tert-Butyl-3-hydroxypiperidine-1-carboxylate tert-butyl

(3S) -3-hydroxy piperidine-1-carboxylate tert-butyl

(S) -3-hydroxypiperidine-1-carboxylate

(3S) -3-Hydroxypiperidine, N-BOC echekwabara

(S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine

Njirimara kemịkalụ

Ebe mgbaze: 34-40 Celsius

Ebe esi esi: 292.3± 33.0 °C (buru amụma)

Njupụta: 1.107±0.06 g/cm3(buru amụma)

Fp: 110 Celsius

nchekwa okpomọkụ: Debe n'ebe gbara ọchịchịrị, Akara akọrọ, Okpomọkụ ụlọ

solubility: Soluble na methanol.

Pka: 14.74±0.20 (buru amụma)

Ụdị: ntụ ntụ ma ọ bụ kristal ntụ ntụ

Agba: White ruo tan

ọrụ anya: [α]22/D +10.0°, c = 1 na chloroform

InChIKey: UIJXHKXIOCDSEB-QMMMGPOBSA-N

njirimara ihe ize ndụ

1 Nhazi nke ihe ma ọ bụ ngwakọta

Mgbakasị akpụkpọ ahụ, Nkeji 2

Iwe iwe anya, Nkeji 2

Nsị akụkụ ahụ ebumnuche ebumnuche akọwapụtara - mkpughe otu, ngalaba 3

Ihe akara akara 2 GHS, gụnyere nkwupụta ịkpachara anya

Foto (s)  image5
Okwu mgbaàmà Ịdọ aka ná ntị
Okwu(s) egwu H315 na-ebute mgbakasị anụ ahụ

H319 na-ebute oke iwe anya

H335 nwere ike ịkpata mgbakasị iku ume

Nkwupụta(s) ịkpachara anya
Mgbochi P264 saa ... nke ọma mgbe ejirichara ya.

P280 Yiri gloves nchebe / uwe nchebe / nchebe anya / nchebe ihu / nchedo anụ / ...

P261 Zere iku ume uzuzu / uzuzu / gas / alụlụ / vapours / fesa.

P271 Jiri naanị n'èzí ma ọ bụ na mpaghara ikuku nke ọma.

Azịza ya P302+P352 Ọ BỤRỤ NA AKWỤKWỤKWỤKWỤKWỤKWỌ AKWỤKWỌ:

Ọgwụgwọ akọwapụtara P321 (lee ... na labelụ a).

P332+P317 Ọ bụrụ na mgbakasị ahụ akpụkpọ emee: Nweta enyemaka ahụike.

P362+P364 Yipụ uwe emerụrụ emerụ ma saa ya tupu ejigharịa ya.

P305+P351+P338 Ọ BỤRỤ NA ANYỊ: Jiri nlezianya sachaa mmiri ruo ọtụtụ nkeji.Wepu lensị kọntaktị, ọ bụrụ na ọ dị ma dị mfe ime.Gaa n'ihu na-asachapụ.

P304+P340 Ọ BỤRỤ na a na-ekunye ya: Wepụ mmadụ n'ikuku dị mma ma nwee ahụ iru ala maka iku ume.

P319 Nweta enyemaka ahụike ma ọ bụrụ na ahụ adịghị gị mma.

Nchekwa P403+P233 Chekwaa n'ebe ikuku na-ekpo ọkụ.Debe akpa ahụ nke ọma.

Akpọchiri ụlọ ahịa P405.

mkpofu P501 Tụfuo ọdịnaya/akpa n'ebe ọgwụgwọ kwesịrị ekwesị na ebe mkpofu dịka iwu na ụkpụrụ siri dị, yana njirimara ngwaahịa n'oge mkpofu.

3 Ihe egwu ndị ọzọ na-adịghị ebute nhazi

enweghị data dị

Nkọwapụta ngwaahịa

Ọdịdị/agba Na-acha ọcha ruo na-acha ọcha siri ike
Ọ nwere ike ịbụ agglomerate mgbe ịchekwaa ogologo oge
njirimara (IR) kwekọrọ
Nyocha (HPLC w/w) 97.0% -103.0%
Ọcha kemịkalụ (mpaghara GC) 99.0%
Ịdị ọcha adịghị ọcha (GC w/w) 3-Hydroxypiperidine0.1%
3-Hydroxypyridine0.20% Achọpụtaghị
1-Boc-3-piperidone0.10% Achọpụtaghị
1-Boc-4-hydroxypiperidine0.10% Achọpụtaghị
1.96RRRT0.2% Achọpụtaghị
Ọdịghị ọcha ọ bụla akọwapụtaghị0.08% 0.01%
Chiral ịdị ọcha (mpaghara HPLC) 99.5%
Methanol (GC) ﹦ 50ppm
Ethanol (GC) ﹦ 50ppm
DCM(GC) ﹦ 500ppm
Mmiri (KF vol w/w) 0.5%

Uru anyị

1: Anyị factory ghọtara na nnukwu commercialized n'ichepụta kemgbe afọ 2012, kwa afọ ahịa ego ruru ihe karịrị 20tons.
2 Ọ bụ onye na-eweta ihe ruru eru maka ụlọ ọrụ ọgwụ patent nke Ibrutinib.
3 Ogo ngwaahịa dị oke mma: nyocha: 97.0% -103.0%
Chemical ịdị ọcha (mpaghara GC): ﹦ 99.0%
Ọdịghị ọcha ọ bụla akọwapụtaghị ﹤ ﹦ 0.08%
Chiral ịdị ọcha (mpaghara HPLC): ﹥ ﹦ 99.5%
4 A na-eme ya site na usoro Mkpebi Chemical.
5 A kwadoro usoro nnwale niile.
6 Otu ụlọ ọrụ raara onwe ya nye maka ime ya.


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